StudentShare
Contact Us
Sign In / Sign Up for FREE
Search
Go to advanced search...
Free

Epidemiologic Study design - Essay Example

Cite this document
Summary
The characteristics of the three study designs were discussed together with their main strength(s) and limitation(s). The most appropriate measure(s) of…
Download full paper File format: .doc, available for editing
GRAB THE BEST PAPER92% of users find it useful
Epidemiologic Study design
Read Text Preview

Extract of sample "Epidemiologic Study design"

RUNNING HEAD Study Designs Epidemiologic Study Designs here here July 3, 2009 Epidemiologic Study Designs This paper tackles three epidemiological study designs: case-control study, cohort study and cross-sectional study. The characteristics of the three study designs were discussed together with their main strength(s) and limitation(s). The most appropriate measure(s) of association for each study design was/were also identified.Case Control StudyCharacteristics of a case-control study In a case control study, selection of research subjects is based on whether or not the research subjects have the condition (or disease) under study.

The term case refers to a subject who has the condition, whereas control refers to a subject who does not have the condition. This study design finds good application in epidemiology for investigating conditions which are relatively rare and in conditions with long latency periods. A researcher performs analysis by looking back in time to evaluate the case and control groups in terms of exposure history and indication of characteristics that may put the subjects at risk for developing the condition under study.

Analysis is conducted under the assumption that differences in the history of exposure will explain the occurrence of more cases than controls (Portney and Watkins, 2009).Strengths of a case-control study The two main strengths of case-control studies are: ease in gathering subjects, and their utility to provide estimates which may support causal relationship between risk factors and the condition (disease) in combination with other evidences (Portney and Watkins, 2009).Limitations of a case-control study Case-control studies are, somehow, limited in the sense that there is a possibility of uncertainty in the temporal relationship between the exposure and the condition (disease).

Another limitation in this type of study design is that the proportion of cases and controls in the study is not related to the proportion of cases and controls in the population. Case control studies require further analysis pertaining to the potential for bias (Portney and Watkins, 2009). Moreover, in a case-control study design, control of selection is difficult; it may be applied to the study of only one disease outcome at a time and is usually subject to recall bias (Jekel, Katz and Elmore, 2001).

Measure of association in a case control studyIn a case-control study, neither absolute risk nor odds can not be measured since “it is only possible to calculate risk in a study where subjects have been followed forward in time” (Daly and Bourke, 2000, p. 166). However, Daly and Bourke (2000) revealed that “the cross-product ratio in a case-control study, which legitimately estimates the ratio of the odds of exposure, must also be a valid estimate of the ration of the odds of disease” (p. 167).Cohort StudyCharacteristics of a cohort study A cohort study, which is also called a follow-up study is one in which the investigator selects subjects who have not yet manifested an outcome of interest (a disease or disorder) and follows the chosen subjects to determine whether or not the disease or disorder develops at a later time.

In a cohort study, research subjects are either interviewed or observed to evaluate the presence or absence of risk characteristics or exposures. Cohort studies may be purelydescriptive, but are oftentimes analytic. In this study design, the risk associated with exposure is identified through a comparison of the incidence of the outcome of interest between those who were exposed to the risks and those who were not. Cohort study design is best for examining multiple disoders. (Portney and Watkins, 2009).

Strengths of a cohort study With a cohort study, the onset of a condition can be determined, and this serves as one of its key advances over case-control studies. Since the research subjects are followed forward in time, use of a cohort study allows the definition of relationship between exposure and risk from a established time sequence. Such sequence is a pre-requisite for developing inferences pertaining to contributing variables (Portney and Watkins, 2009). Chort studies also have the advantages of being performed retrospectively or prospectively (Jekel, Katz and Elmore, 2001).

Limitations of cohort study The main limitation of a cohort study design is its non-applicability to rare conditions in the population because of the impracticality of following a large number of subjects for a long time to obtain documentation for a suitable number of case for generalizability of results (Portney and Watkins, 2009). Additionally, this design is time-consuming and costly for prospective studies; and is subject to losses due to follow-up (Jekel, Katz and Elmore, 2001).Measures of association in a cohort study In a cohort study, appropriate measures of association include relative risk, excess risk (also called attributable risk), attributable risk per cent and odds ratio (Daly and Bourke, 2000; Szklo and Nieto, 2007).

Cross-sectional StudyCharacteristics of a cross-sectional study A cross-sectional study investigates the relationship between exposure and the prevalence of disease. There are three ways of looking at the prevalence of a disease: point prevalence, period prevalence and/or lifetime prevalence. Point prevalence refers to the proportion of people with the disease during the time of the study, whereas period prevalence refers to proportion of people with the disease over a past period of time (e. g., the last two years).

Meanwhile, lifetime prevalence refers to the proportion who have the disease during the past and the present. In a cross-sectional study, no time period is specified and does not delimit the investigation to incident cases only (Susser, Sxhwartz, Morabia and Bromet, 2006). Cross-sectional studies are most applicable for the measurement of current health status and in the determination of health practices (Bailey, et al., 2005).Strengths of a cross-sectional study The most important strength of a cross-sectional study is its efficiency over a longitudinal study or a cohort study, since the former is relatively quick and easy to perform (Portney and Watkins, 2009; Bailey, et al., 2005). Since the research subjects are observed or tested only one and at approximately the same time, this type of study design is not threatened by the effects of testing and history (Portney and Watkins, 2009).

Limitations of cross-sectional study The key limitation of the cross-sectional study design is selection. Difficulty is usually experienced in determining the extent to which results of the investigation show the effects of the passing of time against the effects of extraneous sampling variables ((Portney and Watkins, 2009). Further, temporal relationships can not be determined in a cross-sectional study. The only way that results of cross-sectional studies can be used to test hypotheses in epidemiology is when exposure status does not differ with the passage of time Moreover, since these studies also include prevalent cases, potential bias is seen towards subjects with chronic disease because those with acute and fatal illnesses would have already died before the survey and, therefore, would not have been included (Bailey, et al., 2005).Measures of association in a cross-sectional study The most appropriate measures of association for a cross sectional study are prevalence difference, prevalence ratio and prevalence odds ratio (Susser, et al., 2006). ReferencesBailey, L.

, Vardulaki, K., Langham, J. & Chandramohan, D. (2005). Introduction to epidemiology. New York: McGraw Hill-International.Daly, L. E. & Bourke, G. J. (2000). Interpretation and uses of medical statistics. 5th ed. Oxford: Blackwell Science Ltd.Jekel, J. F., Katz, D. L. & Elmore, J. G. (2001). Epidemiology, biostatistics and preventive medicine. 2nd ed. Philadelphia, PA: Saunders. Portney, L. G. & Watkins, M. P. (2009). Foundations of clinical research: Applications to practice. 3rd ed. Upper Saddle River, NJ: Pearson Education, Inc.Susser, E. S.

, Schwartz, S., Morabia, A. & Bromet, E. J. (2006). Psychiatric epidemiology: searching for the causes of mental disorders. New York: Oxford University Press.Szklo, M. & Nieto, F. J. (2007). Epidemiology. 2nd ed. Sudbury, MA: Jones and Bartlett Publishers.

Read More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Epidemiologic Study design Essay Example | Topics and Well Written Essays - 500 words”, n.d.)
Retrieved from https://studentshare.org/miscellaneous/1556056-epidemiologic-study-design
(Epidemiologic Study Design Essay Example | Topics and Well Written Essays - 500 Words)
https://studentshare.org/miscellaneous/1556056-epidemiologic-study-design.
“Epidemiologic Study Design Essay Example | Topics and Well Written Essays - 500 Words”, n.d. https://studentshare.org/miscellaneous/1556056-epidemiologic-study-design.
  • Cited: 0 times

CHECK THESE SAMPLES OF Epidemiologic Study design

Logistics of International Workers to Mitigate Ebola Epidemics

One of the most important functions of human resource management practices is making decisions that enhance the welfare of human resources in organisations.... Across various industries, human resources are the most important for the success of any business organisation in any… An organisation has to make sure that the welfare of its workers is given first priority over company practices....
4 Pages (1000 words) Case Study

The Increase in the Frequency of Involvement of Ex-Mental Patients in the Criminal Justice System

nbsp; The objective of this study is to determine the effect of deinstitutionalization on the frequency of involvement of ex-mental patients in the criminal justice system through an analysis or review of available data and information on private and public mental hospital capacities, and crime rates in purposively selected U....
10 Pages (2500 words) Case Study

Evolutionary and Historical Aspects of the Burden of Malaria

The case study "Evolutionary and Historical Aspects of the Burden of Malaria" states that With approximately 2.... billion people living under the threat of infection, malaria is considered a global burden that affects a third of the world's population (Snow et al, 2005).... nbsp;… If science reveals no harm from exposures, the policy can be flexible enough to accommodate the change....
9 Pages (2250 words) Case Study

Portfolio for Community Health Nurses

The main idea of this study under the title "Development on post-partum Depression" touches on children's physiologic changes and the influence of community nurses who are in closest contact with them.... The author analyses explain the role of the nurse in these situations....
8 Pages (2000 words) Case Study

Classification of Lung Cancer

The study "Lung Cancer" discusses the most common and deadliest type of cancer - lung cancer.... In classifying lung cancer, the study shows that it can be broadly categorized into two main categories based on the microscope appearance of cancer.... The paper highlights the main categories and types of lung cancer, the processes, which cause this disease, the common lung cancer symptoms, treatment, prevalence, trends, and future projections....
8 Pages (2000 words) Case Study

The Relationship Between Memory Performance and Mental Ability

The study suggested that language level, age and gender are important predictors of poor mental ability, which in turn influence memory performance of students.... In our present study, the participants were sourced from the following areas: a machine plant with 22 registered staffs, a chemical plant with 30 staffs, and a college with 28 trainers and 10 assistant works....
8 Pages (2000 words) Case Study

The Efficiency and Long-Term Effects of Oral Contraceptives

The study used the prospective cohort study design throughout the research in order to examine the results of the data.... The aim of the study was to find out whether oral contraceptives use was associated with mortality that was cause-specific or one that was all-cause among the two main study populations.... nbsp;The research is based on a longitudinal study of 121,701 women for a period of 36 years....
12 Pages (3000 words) Case Study

Use of Sunscreen and Melanoma

This implies that it is difficult to collect accurate data from the population under study regarding their sunscreen usage habits.... The study concludes that men with lower educational levels and those in the youngest age group are less frequent users of sunscreen compared to the whole population.... A study has shown that it is very common amongst youngsters between the age of 11 and 18 to get sunburns....
19 Pages (4750 words) Case Study
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Contact Us