StudentShare
Contact Us
Sign In / Sign Up for FREE
Search
Go to advanced search...

Rhabdomyolysis - Term Paper Example

Cite this document
Summary
Rhabdomyolysis [Name] [Institution] Rhabdomyolysis Introduction Rhabdomyolysis is a clinical syndrome that is usually characterized by the necrosis of muscles as well as the release of potentially toxic intracellular constituents of muscles into the circulatory the system…
Download full paper File format: .doc, available for editing
GRAB THE BEST PAPER98.5% of users find it useful
Rhabdomyolysis
Read Text Preview

Extract of sample "Rhabdomyolysis"

Download file to see previous pages

However, the severity of the syndrome normally range from asymptomatic rise in serum muscle enzymes to the presence of life threatening complications associated with extreme electrolyte imbalances, enzyme elevations as well as acute renal injury (Knochel, 2003). Although Rhabdomyolysis is often common among individuals who have suffered trauma or major injuries, the clinical condition has also been known to develop as a response to particular medications, drugs and dietary supplements. This paper discusses the history and physical findings of rhabdomyolysis, the background of the disease, its etiology, pathogenesis, natural history and management.

History and Physical Findings of Rhabdomyolysis The patient in this medical case study was a 24 year old female who was displaying symptoms consistent with rhabdomyolysis. The clinical history revealed that the patient had taken statin medications to help lower her cholesterol levels and this resulted into a severe muscle pain. Immediately after taking the medication, the patient also suffered from severe muscle weakness, extreme muscle aching throughout her entire body and the production of dark colored urine.

Although the dose of statin dose taken was not high, the patient had also taken another drug known as meofibrozil(Lopid) which could have aggravated the condition((Baxter and Moore, 2003). On the other hand, further inquiry revealed that the patient normally uses nutritional supplements as part of their weight reduction strategies. Confirmatory diagnosis was carried out by using a number of standardized examinations to show the damaged skeletal muscles. Some of the tests carried out included analysis of the patient’s urine, urine myoglobin test, analysis of Creatine kinase level and serum potassium level analysis.

The treatment of the patient included giving her fluids that particularly those containing bicarbonate in order to prevent the potential kidney damage by flushing the remnants of myoglobin from the kidneys (Baxter and Moore, 2003). Additionally diuretic and bicarbonate medicines were also prescribed. After fluid resuscitation, the patient was transferred to a medical facility where measures were also taken to correct potential electrolyte imbalance in the patient. For example, ECG was obtained to help monitor any likely effects of hyperkalemia or other electrolyte imbalances.

Background of the Disease Disease Etiology and Pathogenesis The etiology of rhabdomyolysis is normally broadly categorized into acquired and hereditary causes. Hereditary causes of rhabdomyosis largely consist of enzyme related defects that often result in disorders such as mitochondrial lipid metabolism, carbohydrates metabolism as well as other important inherited disorders such as neuroleptic malignant disorders and hyperthermia. On the other hand, acquired causes generally result from any condition that potentially damages the skeletal muscles such as crush injuries, muscle tremors due to alcoholism, drugs such as statin, cocaine, heroin and amphetamine, extreme exercises, ischemia and trauma (Brancaccio and Lippi, 2010).

Excessive intake of alcohol and other commonly abused drugs such as heroin, cocaine and amphetamines has also been known to result in severe damage to skeletal muscles thereby triggering rhabdomyolysis. Additionally individuals who routinely use nutritional supplements and performance enhancing drugs such as anabolic steroids may also develop rhybdomyolysis which

...Download file to see next pages Read More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Rhabdomyolysis Term Paper Example | Topics and Well Written Essays - 1250 words”, n.d.)
Retrieved from https://studentshare.org/biology/1497139-rhabdomyolysis
(Rhabdomyolysis Term Paper Example | Topics and Well Written Essays - 1250 Words)
https://studentshare.org/biology/1497139-rhabdomyolysis.
“Rhabdomyolysis Term Paper Example | Topics and Well Written Essays - 1250 Words”, n.d. https://studentshare.org/biology/1497139-rhabdomyolysis.
  • Cited: 0 times

CHECK THESE SAMPLES OF Rhabdomyolysis

Electrolytes disorders, hyperkalemia, hypercalcemia, and hpyernatremia, and how they effect our body system

Disease conditions such as Rhabdomyolysis, trauma and hypothermia are few examples that compromise the ability of the cell to withhold potassium within its membranes.... Electrolytes disorders, hyperkalemia, hypercalcemia, and hypernatremia, and how they affect our body system: Introduction: Body fluids mostly comprise of water and electrolytes....
5 Pages (1250 words) Research Paper

Diet Pills: Contents, Risks, Efficacy and Recommendations

Stimulating and energy-spending supplements with Ephedra alkaloids and caffeine increase the risk of stroke, myocardial arrhythmias and hypertension while supplements for controlling the carbohydrate metabolism like ginseng and chromium may produce a lot of damaged free radicals and Rhabdomyolysis....
3 Pages (750 words) Research Paper

Pharmacologic Treatment of Metabolic Syndrome

Pharmacologic Treatment of Metabolic Syndrome Name: Institution: Introduction The conception of metabolic syndrome has subsisted for the past eight decades.... Metabolic syndrome is a frequent metabolic disease that is a result of increased obesity (Blaha & Tota-Maharaj, 2012).... hellip; The pathophysiology of the disease is largely credited to insulin opposition with extreme instability of fatty acids incriminated....
5 Pages (1250 words) Essay

Rapid Sequence Intubation of Patient with Bleeding Tonsillitis

Tonsillectomy is one of the most common surgical procedures performed.... Over 144000 such surgeries have been performed in the US alone.... One of the most feared complications of this surgery includes post surgical bleeding.... About 1% -4% of patients are reported to have a complications related to bleeding after tonsillectomy....
5 Pages (1250 words) Essay

The Effect of Stanol-Sterol on the Lipid Profile of Patients Who Have Undergone Renal Transplantation

But a potential pharmacokinetic interaction with cyclosporine and a resultant increase in the risk of myopathy or Rhabdomyolysis and also reduced renal elimination influence the dose to be used.... The aim of the current study is to study the effect of stanol/sterol, alone or in addition to other agents, on the lipid profile of patients who have undergone renal transplantation and to assess their acceptability as a treatment alternative or adjunct to statin therapy....
6 Pages (1500 words) Assignment

Body Modification through Nutrition and Supplementation

discusses that ability of supplements to increase muscle power can result into muscle complications such as Rhabdomyolysis.... Rhabdomyolysis relates to tear of muscle fibers due to excessive exercise resulting into damage of kidneys and muscle fiber components absorption by the bloodstream.... It is imperious to note that excessive consumption of supplements by athletes for gaining muscle power inherently causes Rhabdomyolysis....
2 Pages (500 words) Essay

Preventing Renal Failure in Patients with Rhabdomyolysis

This paper “Preventing Renal Failure in Patients with Rhabdomyolysis” reviews the incidence, pathophysiology, clinical characteristics, diagnostic methods, advanced practice methods and research implications of Rhabdomyolysis.... Rhabdomyolysis is a cellular syndrome.... hellip; The author states that Rhabdomyolysis has many causes, including cocaine abuse, trauma, strenuous exercise, infections, hyperthermia and other conditions that alter electrolyte balance or disrupt the integrity of the plasma cell membrane....
14 Pages (3500 words) Assignment

Physiology of Addiction

This article explores the physiological and neurobiological aspects of addiction to bring about an understanding of the behavior of addiction.... Addiction is due to many complex factors and is important to treat and conduct research on pharmacotherapeutics.... hellip; This research begins with the statement that addiction of various substances which act on the central nervous system is a major social and health problem....
10 Pages (2500 words) Research Paper
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Contact Us