Essays on DisseminTING EVIDENCE Term Paper

DISSEMINTING EVIDENCE DISSEMINTING EVIDENCE Central venous catheters (CVCs) are largely used in medical practice worldwide, andnot considering the differences among the variety of types of CVCs, and they lead to raising the threat of venous thromboembolism. CVC-associated venous thromboembolism is a primary clinical problem in terms of loss of venous access, the risk of pulmonary embolism, and additional costs (Mazher et.al., 2013).
This factor may have intensified significance in patients suffering from cancer, in which the requirement for CVC insertion is merged with an inherent increased of tumor-related venous thromboembolism (DeVries, et.al., 2014).However, the issue of how to decrease the risk of venous thromboembolism in those kind patients with CVCs is not insignificant. Certainly, the projected advantage of any prophylactic treatment is highly reliant on the complete risk of venous thromboembolism. A value that differ depending upon the type of tumor and clinical presentation such as , pancreatic cancer or mediastinal syndrome. A number of investigators have discovered if anticoagulant therapies (low-molecular-weight heparin or vitamin K antagonists) may inhibit CVC-associated venous thromboembolism. In broad, such investigations have however sustained the systematic use of anticoagulation in that kind of patients, but there are some conflicting data (Danielson, et.al, 2014).
The existence of a central venous catheter (CVC) becomes the primary risk factor for the development of bloodstream infection, mostly in immunocompromised patients. This is especially contamination that is a risk factor for central line-associated bloodstream infection (CLABSI).This observational before-after trial in a major care hospitals oncology unit incorporated adult patients with a CVC. Throughout the period of intervention, the attempt of central line hub care was distorted from clean-up with alcohol wipes towards the use of alcohol-impregnated port protectors. To facilitate the protectors, the needless hubs were changed to a neutral pressure connector (Hong et.al., 2013).
In comparing infection rates when using port protectors’ from scrubbing the hub for 15 seconds, it has been perceived that: It has been perceived that alcohol alone has the efficacy of 70% as compared to 15% chlorhexidine/70% alcohol used for 15 seconds. Investigators also required finding out whether the design of a mechanical valve delay its capability to be appropriately disinfected. Totality 300 mechanical valves from four different kinds were immunized with a 105 colony-forming unit (CFU) suspension of the organisms most commonly available in clinical. Entire valves were flushed with 0.5 ml saline solution; the flush was gathered onto blood agar plates that were incubated for a period of 48 hours to induce bacterial growth (Kaye, et.al., 2011).
After the result, it was concluded that the execution of alcohol-impregnated port protectors and needleless neutral pressure connectors extensively decreased the intensity of CLABSIs and CBCs in our oncology population of the patient (Bull, 2014)

References
Bull, P. (2014). Evaluation of a continuous passive disinfection cap on central line-associated bloodstream infections, contamination and colonization. American Journal of Infection Control, 42, S79-S79.doi:10.1016/j.ajic.2014.03.184
Danielson, B., Williamson, S., Kaur, G., & Johnson, N. (2014). A Significant Decline in Central Line-associated Blood Stream Infections Using Alcohol-impregnated Port Protectors at a Large Non-profit Acute Care Hospital. American Journal Of Infection Control, 42S16. doi:10.1016/j.ajic.2014.03.056
DeVries, M., Mancos, P. S., & Valentine, M. J. (2014). Reducing bloodstream infection risk in central and peripheral intravenous lines: Initial data on passive intravenous connector disinfection. Journal of the Association for Vascular Access, 19(2), 87-93. doi:http://dx.doi.org.library.gcu.edu:2048/10.1016/j.java.2014.02.002
Hong, H., Morrow, D., Forbes, Sandora, T., J., &Priebe, G., P. (2013). Disinfection of needleless connectors with chlorhexidine-alcohol provides long-lasting residual disinfectant activity. American Journal of Infection Control, 41(8), e77-9. doi:10.1016/j.ajic.2012.10.018
Kaye, G., & Mateo, C. (2011). EB92: Multifaceted Initiatives to Eliminate Central Catheter-Associated Blood Stream Infections in the Intensive Care Unit. Critical Care Nurse, 31(2), e35.
Mazher, M. A., Kallen, A., Edwards, J. R., &Donlan, R. M. (2013). An in vitro evaluation of disinfection protocols used for needleless connectors of central venous catheters. Letters in Applied Microbiology, 57(4), 282-287.doi:10.1111/lam.12108